Drug-transporter mediated interactions between anthelminthic and antiretroviral drugs across the Caco-2 cell monolayers
نویسندگان
چکیده
منابع مشابه
Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter
The SLC22A1 influx transporter is expressed on the basolateral membrane of hepatocytes and is involved in the excretion of numerous cations. Inhibition of SLC22A1 by several antiretrovirals, such as the protease inhibitor darunavir, has not previously been determined. In order to better understand and predict drug-SLC22A1 interactions, a range of antiretrovirals were screened for SLC22A1-associ...
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ژورنال
عنوان ژورنال: BMC Pharmacology and Toxicology
سال: 2017
ISSN: 2050-6511
DOI: 10.1186/s40360-017-0129-6